Diabetes mellitus is due to either the pancreas not producing enough insulin or the cells of the body not responding properly to the insulin produced. Diabetic Nephropathy is a chronic kidney disease in those with diabetes mellitus characterized by damage to the capillaries in the the filtering units of the kidney due to abnormal blood glucose levels. It is usually slowly progressive over years.
Progression of diabetic nephropathy
In this recent study, rats who benefited from nutritional supplementation in form of a green tea extract rich in EGCG, a green tea catechin is one such phytochemical which possesses hypoglycemic and antifibrotic activity, experienced an improvement of their renal functions. In accordance with this study, although a number of potential treatment strategies exist for diabetic nephropathy, considering the ease of use and bioavailability, EGCG might be regarded as a prospective therapeutic candidate in modulating diabetic nephropathy, thus being a promising treatment. (1)
Prevention involves maintaining a healthy diet, regular physical exercise, a normal body weight, and avoiding use of tobacco.
Drinking organic green tea on a regular basis can also be a good idea. Green tea species are not all equal, and some may be more beneficial than others.
Impact of EGCG Supplementation on the Progression of Diabetic Nephropathy in Rats: An Insight into Fibrosis and Apoptosis
Thangarajeswari Mohan† , Prema Velusamy†, Lakshmi Narasimhan Chakrapani†, Ashok Kumar Srinivasan†, Abhilasha Singh†, Thanka Johnson‡, and Kalaiselvi Periandavan*†
† Department of Medical Biochemistry, Dr ALMPGIBMS, University of Madras, Taramani Campus, Chennai, India
‡ Department of Pathology, Sri Ramachandra University, Chennai, India
1. Agric. Food Chem., Article ASAP
Publication Date (Web): August 21, 2017
Copyright © 2017 American Chemical Society